The number of people living with diabetes has soared by nearly 60% in the past decade, Diabetes UK warns.
The charity said more than 3.3 million people have some form of the condition, up from 2.1 million in 2005.
The inability to control the level of sugar in the blood can lead to blindness and amputations and is a massive drain on NHS resources.
Diabetes UK called for the NHS to improve care for patients and for greater efforts to prevent diabetes.
Roughly 90% of cases are type 2 diabetes, which is the form closely linked to diet and obesity.
People with type 1 generally develop it in childhood and are unable to produce the hormone insulin to control their blood sugar levels.
Dr Joan St John, a GP in Brent in north-west London, where diabetes levels are some of the highest in the country, said the condition had become incredibly widespread.
She told the BBC News website: “It’s very noticeable in that not a week goes by that you don’t make a new diagnosis of diabetes, at least one or sometimes two or three; previously that might have been one a month.”
The complications of uncontrolled blood sugar levels can be severe, including nerve damage, loss of vision and organ damage.
The condition even leads to 135 foot amputations every week across the country.
Dr St John added: “Unfortunately that historical myth that it is not a serious condition is still retained by some people and you have to dispel that myth.”
“One of the most miserable complications is neuropathy [nerve damage] which can cause a constant nagging, gnawing ache, usually in the legs or feet, and this can be really disturbing and there is no cure for it,” she added.
Data published last week showed that diabetes medication now accounts for 10% of the NHS drugs bill.
Nearly £869m was spent on drugs, including insulin and metformin, marking a sharp rise from the £514m being spent a decade ago, when the drugs accounted for just 6.6% of the prescriptions budget.
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